Lovecraft tales are known for the hopelessness and insanity that overcome humanity, the title has too much comedy (in the form of nonstop gritty wisecracking) and an unrealistic superman all-around tough guy but still a good guy sort of thing going on for my tastes. If I find myself rooting against the protagonist, then the whole idea of a future dominated by Cthulhu misses the mark.
These sort of characters, are in my opinion. better suited to military science fiction series where the details about wars and campaigns give the reader a break from too much dialogue by shallow, stereotypical characters.
Great concept, and it started off well, but became too predictable. Why NOT have him married off to a 72-year old administrator instead of a standard hot exotic mutant since it wasn’t his choice? Why does the ghoul have to be 1980s comic relief in a Hawaiian shirt? I never felt like the main character was in any danger after the initial encounter in the cathedral. It created a predictable boring sort of read.